What causes colic?

Whilst there may be several causes, the role of gut microbiota has come into focus recently.

Colicky infants have been seen to have lower number of certain types of healthy bacteria (Lactobacilli) in their digestive system compared to healthy infants.


Differences in microbiota composition in colicky and non colicky infants.

Lower counts of intestinal lactobacilli species in colicky infants compared to non-colicky ones.
Higher counts of coliforms, especially E. coli, in colicky infants compared to non-colicky ones.

Colic can also be attributed to other factors like underdeveloped gut movement which can lead to gassiness and pain.

Dr. Flavia Indrio
Department of Paediatrics
University of Bari, Italy

“Colic, regurgitation and constipation can be prevented through early intervention with BioGaia L. reuteri DSM 17938”

Dr. Flavia Indrio recommend microbial transfer from mom to newborns for at least 1000 days from conception to 2 years after birth for the life-long health of the child.


First try to keep your spirit up and stay calm though it may be hard. Remember, there is nothing you have done wrong that has caused the colic. And usually it will gradually gets better within 3 to 4 months.


FGIDs during the first year of life

Research shows that BioGaia powerful patented strain Lactobacillus reuteri DSM 17938 is safe for babies and is found naturally in the intestinal tracks of babies and in some breast milk. It has significant effects on Functional Gastro Intestinal Disorders (FGIDs) and protection of infection in infants and children.

It reduces visceral pain by releasing of neuromodulating molecules. It also influences the intestinal microbiota by releasing reuterin, lactic acid and acetic acid, which help to promote growth of other good bacteria, and inhibit the bad bacteria thus restoring gut health.

Other health benefits from a healthy gut is the reduction of ‘leaky gut’ and increase intestinal cell growth, faster replacement of wounded intestinal cell thus resulting in improved immunity.


There are studies to link colic with inflammation. Left untreated colic can lead to other functional gastro intestinal disorder like Gerd (gastroesophageal reflux disease), CMP allergy (eg. cow milk allergy), aerophagia (excessive air swallowing), gut microflora imbalance, inadequate gut hormone secretion especially in the first twelve months of life and other neurological disorder (like migraine), psychological disorders, developmental delays later in life.


95% infants response to treatment.
50% reduction in crying time after one week

How do I use BioGaia
Probiotic Drops?

Ingredients:
Active ingredient
Lactobacillus reuteri DSM 17938

Recommended dose:
5 drops, once daily

100 million CFU per
0.17mL (5 drops)

Storage condition:
Store at room temperature ~25°C
Once opened to refrigerate and use within 3 months.

Note :
Always read the label. Follow directions for use. If symptoms persist or worsen, talk to your health professional.

BioGaia probiotics during pregnancy and early infancy

Newborns acquire their microflora primarily from their mother.

BioGaia is available in chewable tablets for pregnant and lactating moms.
Also suitable for 3 years old and above and other adults.

* Pregnant moms can start on L. reuteri DSM 17938 soonest as new studies suggest that the placenta would already have its own microbiome.

* Recent studies point to taking a good probiotic can help lower risk of preterm birth and preeclampsia condition.

Stay healthy throughout life
with BioGaia probiotics.

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